{"id":72021,"date":"2016-12-15T00:00:00","date_gmt":"2016-12-14T16:00:00","guid":{"rendered":"http:\/\/tnr.com.tw\/2016\/12\/15\/%e8%87%ba%e7%81%a3%e8%a2%ab%e7%a8%b1%e3%80%8c%e6%b4%97%e8%85%8e%e7%8e%8b%e5%9c%8b%e3%80%8d-%e5%a4%9a%e5%b9%b4%e9%ab%98%e5%b1%85%e5%81%a5%e4%bf%9d%e9%86%ab%e7%99%82%e8%b2%bb%e6%94%af%e5%87%ba%e7%ac%ac\/"},"modified":"2016-12-15T00:00:00","modified_gmt":"2016-12-14T16:00:00","slug":"%e8%87%ba%e7%81%a3%e8%a2%ab%e7%a8%b1%e3%80%8c%e6%b4%97%e8%85%8e%e7%8e%8b%e5%9c%8b%e3%80%8d-%e5%a4%9a%e5%b9%b4%e9%ab%98%e5%b1%85%e5%81%a5%e4%bf%9d%e9%86%ab%e7%99%82%e8%b2%bb%e6%94%af%e5%87%ba%e7%ac%ac","status":"publish","type":"post","link":"https:\/\/tnr.com.tw\/?p=72021","title":{"rendered":"\u81fa\u7063\u88ab\u7a31\u300c\u6d17\u814e\u738b\u570b\u300d \u591a\u5e74\u9ad8\u5c45\u5065\u4fdd\u91ab\u7642\u8cbb\u652f\u51fa\u7b2c\u4e00\u540d \u591a\u56ca\u814e\u75c5\u8b8a\u75c5\u60a3\u7d04\u4f54\u6d17\u814e\u60a3\u8005\u4e00\u6210 \u537b\u7121\u85e5\u53ef\u91ab \u81fa\u5e2b\u5927\u3001\u570b\u7814\u9662\u3001\u6210\u5927\u5408\u4f5c \u7814\u767c\u91cd\u7d44\u86cb\u767d\u8cea\u85e5\u7269 \u81ea\u9ad4\u986f\u6027\u591a\u56ca\u814e\u75be\u75c5\u6cbb\u7642\u73fe\u66d9\u5149 \u672a\u4f86\u964d\u4f4e\u6d17\u814e\u60a3\u8005\u73fe\u5e0c\u671b"},"content":{"rendered":"<\/p>\n

\u81fa\u7063\u88ab\u7a31\u70ba\u300c\u6d17\u814e\u738b\u570b\u300d\uff0c\u591a\u5e74\u4f86\u63ee\u4e4b\u4e0d\u53bb\uff0c2015\u5e74\u6d17\u814e\u4eba\u53e3\u7a81\u78348\u842c\u4eba\uff0c\u5065\u4fdd\u652f\u51fa\u9ad8\u9054454\u5104\u5143\uff0c\u5176\u4e2d\u907a\u50b3\u6027\u75be\u75c5\u300c\u591a\u56ca\u814e\u75c5\u8b8a\u300d\u5c0e\u81f4\u6162\u6027\u814e\u8870\u7aed\uff0c\u7d04\u4f54\u6d17\u814e\u60a3\u8005\u76845\u81f310%\uff0c\u537b\u7121\u85e5\u53ef\u91ab\u3002\u5728\u570b\u7acb\u81fa\u7063\u5e2b\u7bc4\u5927\u5b78\u3001\u570b\u5bb6\u5be6\u9a57\u7814\u7a76\u9662\u570b\u5bb6\u52d5\u7269\u4e2d\u5fc3\u53ca\u6210\u529f\u5927\u5b78\u5408\u4f5c\u4e0b\uff0c\u7814\u767c\u91cd\u7d44\u7684\u86cb\u767d\u8cea\u85e5\u7269\uff0c\u6ce8\u5c04\u81f3\u591a\u56ca\u814e\u75be\u75c5\u9f20\u9ad4\u5167\uff0c\u8b49\u5be6\u6709\u6548\u6e1b\u7de9\u75be\u75c5\u60e1\u5316\uff0c\u58fd\u547d\u4e5f\u5f9e\u539f\u672c25\u5929\u5ef6\u9577\u70ba170\u5929\u3002\u6574\u500b\u7814\u7a76\u6b77\u7a0b\u8017\u664213\u5e74\uff0c\u4e0b\u968e\u6bb5\u5c07\u9032\u884c\u81e8\u5e8a\u524d\u591a\u56ca\u814e\u75be\u75c5\u5927\u9f20\u6a21\u5f0f\u7684\u6cbb\u7642\u5be6\u9a57\uff0c\u4ee5\u671f\u76e1\u5feb\u9032\u5165\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\uff0c\u70ba\u6cbb\u7642\u591a\u56ca\u814e\u75c5\u8b8a\u5e36\u4f86\u66d9\u5149\u3002<\/p>\n<\/p>\n

\u3000\u81ea\u9ad4\u986f\u6027\u591a\u56ca\u814e\u75be\u75c5(Autosomal Dominant Polycystic Kidney Disease;\u7c21\u7a31ADPKD)\u662f\u76f8\u7576\u5e38\u898b\u7684\u907a\u50b3\u75be\u75c5\uff0c\u76db\u884c\u7387\u7d04\u4e94\u767e\u5206\u4e4b\u4e00\uff0c\u5168\u7403\u75c5\u60a3\u7d041\u5343200\u842c\u4eba\uff0c\u76ee\u524d\u4e26\u7121\u6709\u6548\u7684\u6cbb\u7642\u85e5\u7269\uff0c\u75c5\u4eba\u5e73\u5747\u7d0440\u6b72\u56e0\u4e0b\u80cc\u75db\u5408\u4f75\u8840\u5c3f\u5c31\u8a3a\uff0c\u4ee5\u8d85\u97f3\u6ce2\u53ef\u4ee5\u770b\u5230\u814e\u81df\u9577\u51fa\u8a31\u591a\u56ca\u6ce1\uff0c\u5e73\u5747\u60e1\u5316\u81f350\u6b72\uff0c\u591a\u6578\u75c5\u60a3\u5c31\u9700\u4f9d\u8cf4\u6d17\u814e\u548c\u814e\u81df\u79fb\u690d\u4f86\u7dad\u6301\u751f\u547d\u3002<\/p>\n<\/p>\n

\u3000\u4f9d\u5065\u4fdd\u7f72\u516c\u5e03\u7684\u4f7f\u7528\u6700\u591a\u5065\u4fdd\u9580\u8a3a\u91ab\u7642\u8cbb\u7528\u7684\u524d20\u5927\u75be\u75c5\uff0c\u591a\u5e74\u4f86\u4ee5\u6162\u6027\u814e\u8870\u7aed\u9ad8\u5c45\u7b2c\u4e00\u4f4d\uff0c\u800c\u4e14\u6d17\u814e\u4eba\u53e3\u9084\u5e74\u5e74\u6301\u7e8c\u6210\u9577\uff0c\u6839\u64da\u5065\u4fdd\u7f722015\u5e74\u7d71\u8a08\uff0c\u5168\u81fa\u6d17\u814e\u60a3\u8005\u5df2\u7a81\u78348\u842c\u4eba\uff0c\u4e00\u5e74\u5065\u4fdd\u652f\u51fa\u9700\u8981\u82b1\u8cbb\u7d04454\u5104\u5143\uff0c\u5176\u4e2d\u81ea\u9ad4\u986f\u6027\u591a\u56ca\u814e\u75c5\u7d04\u4f545-10%\u3002\u4ee5\u81fa\u7063\u548c\u7f8e\u570b\u70ba\u4f8b\uff0c\u9019\u985e\u75c5\u60a3\u6bcf\u5e74\u8017\u640d\u91ab\u7642\u7d93\u8cbb\u5206\u5225\u7d0434\u5104\u81fa\u5e63\u548c20\u5104\u7f8e\u91d1\u3002<\/p>\n<\/p>\n

\u3000 \u570b\u7acb\u81fa\u7063\u5e2b\u7bc4\u5927\u5b78\u751f\u547d\u79d1\u5b78\u7cfb\u8b1d\u79c0\u6885\u6559\u6388\u8207\u570b\u5bb6\u5be6\u9a57\u7814\u7a76\u9662\u570b\u5bb6\u52d5\u7269\u4e2d\u5fc3\u53ca\u6210\u529f\u5927\u5b78\u5408\u4f5c\u7684\u7814\u7a76\u5718\u968a\uff0c\u65e5\u524d\u63a1\u7528\u8207\u4eba\u985e\u591a\u56ca\u814e\u75be\u75c5\u76f8\u540c\u7684Pkd1<\/em>\u57fa\u56e0\u7a81\u8b8a\u7684\u591a\u56ca\u814e\u75be\u75c5\u6a21\u5f0f\u9f20\uff0c\u904b\u7528\u57fa\u56e0\u8f49\u6b96\u65b9\u5f0f\uff0c\u8b93\u75c5\u9f20\u5927\u91cf\u8868\u9054\u55dc\u4e2d\u6027\u767d\u8840\u7403\u81a0\u539f\u86cb\u767d\u8cea?\u76f8\u95dc\u758f\u6c34\u6027\u86cb\u767d\u8cea (Neutrophil gelatinase-associated lipocalin;\u7c21\u7a31NGAL)\uff0c\u7d50\u679c\u767c\u73feNGAL\u86cb\u767d\u53ef\u4ee5\u986f\u8457\u6539\u5584\u75c5\u9f20\u75c7\u72c0\uff0c\u5305\u62ec\u6e1b\u7de9\u56ca\u6ce1\u751f\u9577\u53ca\u814e\u81df\u7d44\u7e54\u7e96\u7dad\u5316\uff0c\u9032\u800c\u5ef6\u9577\u58fd\u547d\u3002\u7814\u7a76\u5718\u968a\u4e5f\u9032\u4e00\u6b65\u904b\u7528NGAL\u91cd\u7d44\u86cb\u767d\u8cea\u6cbb\u7642\u591a\u56ca\u814e\u75be\u75c5\u9f20\uff0c\u66f4\u52a0\u8b49\u5be6NGAL\u91cd\u7d44\u86cb\u767d\u8cea\u53ef\u4ee5\u986f\u8457\u5730\u6e1b\u7de9\u75be\u75c5\u60e1\u5316\u4e26\u5ef6\u9577\u75c5\u9f20\u7684\u58fd\u547d\u3002<\/p>\n<\/p>\n

\u3000\u7814\u7a76\u5718\u968a\u9996\u5ea6\u63ed\u793aNGAL\u6539\u5584\u591a\u56ca\u814e\u76f8\u95dc\u75c5\u7406\u6a5f\u5236;\u53ef\u80fd\u900f\u904e\u8207\u5176\u53d7\u9ad4\u7d50\u5408\uff0c\u8abf\u63a7\u56ca\u6ce1\u4e0a\u76ae\u7d30\u80de\u4e4b\u51cb\u4ea1\uff0c\u6e1b\u5c11\u814e\u81df\u9593\u8cea\u7d44\u7e54\u7e96\u7dad\u5316\uff0c\u4e5f\u964d\u4f4e\u7279\u5b9a\u8a0a\u606f\u50b3\u5c0e\u8def\u5f91\u9020\u6210\u56ca\u6ce1\u4e0a\u76ae\u7d30\u80de\u751f\u9577\u6e1b\u7de9\uff0c\u5f9e\u800c\u6e1b\u7de9\u75be\u75c5\u60e1\u5316\uff0c\u63d0\u9ad8\u751f\u5b58\u7387\u8207\u58fd\u547d\u3002<\/p>\n<\/p>\n

\u7814\u7a76\u5718\u968a\u66f4\u9032\u4e00\u6b65\u5730\uff0c\u5c07\u88fd\u9020\u7684NGAL\u91cd\u7d44\u86cb\u767d\u8cea\uff0c\u6ce8\u5c04\u81f3\u591a\u56ca\u814e\u75be\u75c5\u9f20\u9ad4\u5167\u3002\u7d50\u679c\u8b49\u5be6\uff0c\u53ef\u4ee5\u6709\u6548\u5730\u6e1b\u7de9\u75be\u75c5\u60e1\u5316\uff0c\u5c07\u75c5\u9f20\u58fd\u547d\u7531\u539f\u672c\u768425\u5929\u5ef6\u9577\u5230\u7d04170\u5929\u3002<\/p>\n<\/p>\n

\u3000\u9019\u9805\u7814\u7a76\u6210\u679c\u5229\u7528\u300c\u86cb\u767d\u8cea\u85e5\u7269\u6982\u5ff5\u300d\u958b\u767c\u51fa\u65b0\u7684\u6cbb\u7642\u85e5\u7269\uff0c\u540c\u6642\u4e5f\u91d0\u6e05NGAL\u86cb\u767d\u8cea\u53ef\u6e1b\u7de9\u591a\u56ca\u814e\u75be\u75c5\u60e1\u5316\u4e4b\u5206\u5b50\u75c5\u7406\u6a5f\u8f49\uff0c\u53d7\u5230\u5b78\u8853\u754c\u91cd\u8996\u3002\u570b\u969b\u814e\u81df\u5354\u6703\u5c08\u696d\u5b98\u65b9\u520a\u7269\u570b\u969b\u814e\u81df\uff08Kidney International<\/em>\uff09\u5df2\u65bc2016\u5e7410\u670827\u65e5\u520a\u767b\u9019\u7bc7\u8ad6\u6587\uff0c\u7db2\u5740\uff1ahttp:\/\/www.kidney-international.org\/article\/S0085-2538(16)30488-4\/fulltext\u3002<\/p>\n<\/p>\n

\u3000\u6709\u5225\u65bc\u4ee5\u5f80\u81ea\u9ad4\u986f\u6027\u591a\u56ca\u814e\u75be\u75c5\u85e5\u7269\u7814\u767c\uff0c\u90fd\u662f\u7528\u975e\u5178\u578b\u591a\u56ca\u814e\u5c0f\u9f20\u6216\u5927\u9f20\u6a21\u5f0f\u505a\u7814\u7a76\uff0c\u96d6\u7136\u90fd\u662f\u814e\u81df\u9577\u6c34\u6ce1\uff0c\u4f46\u662f\u5176\u57fa\u56e0\u7a81\u8b8a\u8207\u4eba\u985e\u591a\u56ca\u814e\u75be\u75c5\u4e26\u4e0d\u76f8\u540c\uff0c\u8abf\u63a7\u7684\u75c5\u7406\u6a5f\u8f49\u4e5f\u4e00\u5b9a\u4e0d\u6703\u76f8\u540c\u3002\u6b64\u5916\uff0c\u6bd4\u8d77\u5316\u5b78\u5408\u6210\u85e5\u7269\uff0c\u86cb\u767d\u8cea\u85e5\u7269\u7684\u526f\u4f5c\u7528\u8f03\u5c11\u4e14\u5c08\u4e00\u6027\u8f03\u9ad8\uff0c\u66f4\u5bb9\u6613\u901a\u904e\u81e8\u5e8a\u8a66\u9a57\uff0c\u662f\u76f8\u7576\u7406\u60f3\u7684\u85e5\u7269\uff0c\u4e5f\u662f\u5168\u7403\u751f\u6280\u767c\u5c55\u7684\u8da8\u52e2\u3002<\/p>\n<\/p>\n

\u3000\u7814\u7a76\u5718\u968a\u5f9e\u6210\u529f\u5730\u5efa\u7acb\u8207\u4eba\u985e\u591a\u56ca\u814e\u75be\u75c5\u76f8\u540c\u7684Pkd1<\/em>\u57fa\u56e0\u7a81\u8b8a\u7684\u75be\u75c5\u6a21\u5f0f\u9f20\u5230\u7814\u767c\u6cbb\u7642\u85e5\u7269\uff0c\u524d\u5f8c\u6b77\u7d9313\u5e74\u3002\u7814\u7a76\u5718\u968a\u6b64\u6b21\u7814\u7a76\u6210\u679c\u5c07\u5e36\u4f86\u6cbb\u7642\u591a\u56ca\u814e\u75c5\u7684\u65b0\u5951\u6a5f\uff0c\u6709\u671b\u964d\u4f4e\u591a\u56ca\u814e\u75c5\u60a3\u5f8c\u671f\u6d17\u814e\u98a8\u96aa\u3002<\/p>\n<\/p>\n

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